🫠 Office Debt Meltdown?
Plus: Pig-to-Human Kidney, Big Dollars in Fighting Aging, and More
Top 5 market, investing, and business insights of the week, from outside the mainstream media, that should be on your radar, along with our top 3 charts.
Let's get to it!
Top 5 Insights of the Week
1. 🏢 Office Debt Meltdown?
Distressed CMBS (Commercial Mortgage-Backed Securities) office debt rose to 10.5%, more than tripling year-over-year, with $46.6 billion due by 2025.
Only 26% of last year's $35.8 billion office loans were fully paid off, showing a common extend-and-pretend approach.
Reliance on rate cuts and occupancy increase may fail, risking distress, especially in regional banks.
2. 🚧 Road Marked Riches
Self-driving cars mean more road painting, boosting line striping business demand.
FHA mandated brighter pavement markings to reduce crashes and aid in self-driving technologies.
Global line striping machine market was $1690.39M in 2022, set to reach $2750.2M by 2031, growing at 5.56% annually.
3. 💊 The Medicine Behind Pig-to-Human Kidney
Surgeons perform first-ever transplant of pig kidney into a human using genetic modification, known as Xenotransplantation.
100,000+ in the U.S. wait for organs, with one added every 9 minutes.
Experimental drug Tegoprubart, developed by Eledon Pharmaceuticals, helped prevent body’s rejection.
Xenotransplantation market to grow to $29.9B by 2032 from $12.7B in 2022.
4. 👴 Big Dollars in Fighting Aging
Within the next decade, new drugs aimed at eliminating aging cells are expected to receive medical approval.
Biotech companies, like Unity Biotechnology, are treating aging as a medical condition.
Altos Labs received $3 billion to research a way to make cells younger.
Non-surgical rejuvenation market is set to hit $11.2 billion by 2027, growing at 8.2% annually from 2022.
5. 🍎 Apple AI June 10th
Apple will unveil its AI strategy at the Worldwide Developers Conference June 10th.
The iOS 18 update, featuring AI, is set to be the biggest revamp in iPhone software history.
Apple is working on its own AI model called "Ajax".
Apple bought 32 AI companies to boost their own AI skills and tech.
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Top 3 Charts of the Week
1. 🔥 AI Domains on Fire
Anguilla's ".ai" domain earned $32 million, 10% of GDP, driven by AI site registrations.
".com" holds 46% market share, but ".ai" is gaining traction.
Google searches for "ai domain" exceeded "com domain" in the past year, signaling a naming shift.
2. 🎙️ Joe Rogan's Podcast Reigns Supreme
Gained in 4 years, boosted by a $100m deal in 2020.
Renewed for $250m, this time no exclusive rights.
Audience skews male (71%) and ages 18-34 (46%), with 46% identifying as Republicans, 31% as Independent, and 23% as Democrats.
3. 🍩 Krispy Kreme's Resurgence
McDonald’s partnership: Krispy Kreme doughnuts to be sold in all ~13,500 US locations by 2026, boosting shares by 39%.
Aiming to expand to ~6,800 other third-party stores to meet demand.
Signals international expansion, eyeing Europe and Brazil.
Over the past year, shares have lagged due to fears of weight loss drugs, such as Ozempic.
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